
Santa Cruz Island Vacations from $449
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The Latest Santa Cruz Island vacation packages
Price found within the past 48 hours. Click for updated prices.


Mi Playa Galapagos Beachfront
Save 100% on your flight
Price was $1,748, price is now $1,156 per person
$1,156
per person
Oct 29 - Nov 3
found 22 hours ago
Roundtrip non-stop flight included
Quito (UIO) to Isla Baltra (GPS)
9/10 Wonderful! (6 reviews)
Great property and location. The hosts were super helpful. Great breakfast!
Reviewed on Jun 1, 2025

La Casa de Marita
Save 100% on your flight
Price was $1,088, price is now $767 per person
$767
per person
Oct 29 - Nov 3
found 22 hours ago
Roundtrip non-stop flight included
Quito (UIO) to Isla Baltra (GPS)
9/10 Wonderful! (97 reviews)
We had a lovely night stay here. You’re on an island so some ants and bugs can be expected. This isn’t The Four Seasons so if you were looking for that you would be disappointed. What you will find staff willing to go above and beyond like Jonathan, who made our stay lovely. Love that you could just walk to the beach right behind the property. The peace and tranquillity you will find here is unmatched. I think this is the best place to stay on the island. We will definitely be returning.
Reviewed on May 14, 2025

Blu Galapagos Sustainable Waterfront Lodge
Save 100% on your flight
Price was $1,187, price is now $837 per person
$837
per person
Nov 27 - Dec 1
found 22 hours ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
8.8/10 Excellent! (115 reviews)
We had a great stay at Blu Galapagos. Loved the location and our room was perfect - Great view, well maintained and had a king bed. Even if the description says queen bed and the picture looks like a king, you can trust the picture. Morning breakfast with iguanas and seals, and all day Galapagos coffee availability made this stay special.
Reviewed on Aug 17, 2025

Angermeyer Waterfront Inn
Price was $905, price is now $645 per person
$645
per person
Nov 27 - Dec 1
found 22 hours ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
9.4/10 Exceptional! (121 reviews)
Beautiful view and very friendly staff. You do have to take a water taxi ($1 and operates 24/7) to the main part of downtown Santa Cruz but the view is worth it! Also it’s across from The Point by Midoro which as an amazing view and food. I would stay there again!
Reviewed on Aug 26, 2025
Don't see what you're looking for?
See all available trips from Columbus to Santa Cruz Island
View all tripsDiscover the most popular places to visit in Santa Cruz Island

Tortuga Bay Beach
5/5(89 reviews)
If a restful vacation is part of your travel plans, Tortuga Bay Beach might be the perfect place to seek out during your trip to Bella Vista. While you're in the area, wander around the parks.

El Garrapatero Beach
4.5/5(28 reviews)
Why not spend a carefree afternoon at El Garrapatero Beach during your travels in El Cascajo? While you're in the area, wander around the parks.

Las Ninfas Lagoon
Commune with nature and explore the great outdoors at Las Ninfas Lagoon during your travels in Puerto Ayora. While you're here, you can savor the top-notch restaurants.
What to do in Santa Cruz Island

Tour of the city to Isabela + Tintoreras from Santa Cruz
$256
per adult

Full Day Tour Pinzon Island + La Fe/Las Palmas - Snorkeling & Fishing
$169
per adult
Santa Cruz Island Hotel Deals

Hotel Fiesta
Calle Moises Brito y Juan Montalvo, Puerto Ayora, Galapagos
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $155 total per night from Sep 20 to Sep 21
$155 total
Sep 20 - Sep 21
9/10 Wonderful! (367 reviews)
"The rooms were very comfortable, the jacuzzi was a very nice surprise for us, the weather was a bit cold so we had a very good time there. It has a very convenient location you can walk to many places. The breakfast was very good and the staff was very kind."
Reviewed on Sep 17, 2025

Hotel el descanso del Guia
Calle Delfin, Barrio el Mirador, Puerto Ayora, Galapagos
$72 nightly
The price is $72 total per night from Sep 29 to Sep 30
$72 total
Sep 29 - Sep 30
8.6/10 Excellent! (167 reviews)
"Muy lindo todo <3"
Reviewed on Aug 19, 2025

Royal Palm Galapagos, Curio Collection Hotel by Hilton
Km. 18 Via Puerto Ayora-Baltra Isla, Isla Santa Cruz, Santa Rosa, Galapagos
$293 nightly
The price is $322 total per night from Sep 20 to Sep 21
$322 total
Sep 20 - Sep 21
9.2/10 Wonderful! (51 reviews)
"The best part about staying at Royal Palms Galapagos was the staff. They were all friendly and helpful, making their best effort to make our stay enjoyable. They remembered our dietary restrictions and would point out if a dish had food we couldn’t eat. The facilities were very nice, and cleaned ..."
Reviewed on Sep 13, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.